Those who favor using CBD oil and other CBD products assert that it has therapeutic uses. This article highlights the benefits of CBD in treating various disorders, including persistent pain, inflammation, migraines, epilepsy, autoimmune diseases, depression, and anxiety.
Cannabidiol, more commonly referred to as CBD, is a molecule in the cannabis sativa plant, sometimes called hemp. It is a plant chemical that doesn’t make you high but has a lot of health advantages. CBD is isolated from the plant. Therefore, it contains little or no psychoactive THC. There are several advantages to taking CBD products. CBD has been shown to offer several health advantages, including treating anxiety, seizures, and even cancer. CBD oils, which may be used to alleviate pain and inflammation, are among the most popular CBD products. CBD is also known to have a wide range of therapeutic characteristics that can be used to treat various health conditions.
The Benefits of Using CBD
Anxiety reduction
CBD may assist with anxiety management. Graczyk et al. (2021) showed that CBD might alter the response of serotonin receptors in the brain, a neurotransmitter associated with mental wellness. Receptors are small proteins connected to cells that receive chemical signals and assist cells in responding to various stimuli. According to Bergamaschi et al. (2011), taking 600mg of CBD before giving a speech helped those with social anxiety perform better.
Anti-seizure
CBD has previously been reported as a potential therapy for epilepsy. Researchers are examining the effectiveness and safety of CBD in reducing the number of seizures in persons with epilepsy. To learn more about cannabidiol’s potential for treating seizure disorders, Millar et al. (2019) administered CBD orally in doses ranging from 2 to 5 milligrams daily to research participants already taking anti-epileptic drugs. Participants in the trial were watched for 12 weeks by the project’s researchers, who recorded any undesirable side effects and evaluated the frequency of seizures they experienced. Overall, individuals experienced 36.5% fewer seizures each month. On the other hand, 12% of subjects experienced serious side effects.
Neuroprotective
To better understand how CBD can benefit people with neurodegenerative disorders, researchers have turned their attention to a receptor in the brain linked to neurodegenerative diseases. According to Fernández‐Ruiz et al. (2013), this receptor is designated CB1 CBD oil. It is being investigated by scientists to treat numerous diseases, including Alzheimer’s, multiple sclerosis (MS), and Parkinson’s disease stroke. CBD oil may help lower inflammation, which can exacerbate neurological symptoms. More research is required to fully comprehend CBD oil’s impact on neurodegenerative illnesses.
Treat Opioid Dependence
According to Hurd et al. (2015), people addicted to opioids may benefit from using cannabidiol (CBD). In one such trial, CBD was delivered to heroin-dependent individuals. CBD dramatically decreased heroin users’ cue-induced cravings, withdrawal anxiety, resting heart rate, and salivary cortisol levels over one week. No severe adverse effects were discovered. VanDolah et al. (2019) indicated that CBD might be a useful treatment for opioid addiction due to its ability to alleviate various psychological and physiological symptoms, such as anxiety, sleeplessness, and pain, in patients with substance use disorders. However, additional research is required.
Alleviate Diabetes Complications
CBD reduces the impact of excessive glucose levels on other cells in the body, which is often a precursor to the development of diabetes and its problems. Weiss et al. (2006) found that CBD could benefit patients with diabetes, diabetic complications, and arterial plaque accumulation. In another minor research, CBD and a placebo were administered to 13 individuals with type 2 diabetes who were not receiving insulin treatment. According to the study, researchers observed that CBD reduced their resistin levels and boosted their glucose-dependent insulinotropic peptide. According to Jadoon et al. (2016), this hormone promotes an adequate insulin release from digested food. CBD may be a natural therapy for diabetes since it helps the body control insulin-related hormone levels.
Anti-acne
CBD’s actions on immune system receptors may lower inflammation in the body. In turn, CBD oil may provide acne-management benefits. According to Peyravian et al. (2022), CBD oil inhibits sebaceous gland activity. These glands produce sebum, a naturally occurring oily fluid that moisturizes skin. However, excessive sebum might cause acne. Consult a dermatologist before using CBD oil for acne therapy. We need more research on how CBD might help acne in humans.
Cancer Therapy
Seltzer et al. (2020) showed the impact of CBD in inhibiting the proliferation of cancer cells, but research is still in its infancy. According to the National Cancer Institute (NCI), CBD may be useful in treating cancer symptoms and side effects. The National Cancer Institute does not completely support using cannabis as a treatment for cancer. CBD’s anti-inflammatory and cell-reproduction modifying properties make it a viable cancer therapeutic agent. CBD inhibits the capacity of certain types of tumor cells to proliferate.
CBD and the Endocannabinoid System
The endocannabinoid system directly impacts the central nervous system and how individuals respond to internal and external stimuli. According to Di Marzo & Piscitelli (2015), CBD and other cannabinoids connect to cannabinoid receptors in the endocannabinoid system. These two primary cannabinoid receptors are found in the central nervous system; CBD attaches to CB1 and CB2 receptors and activates them, which is how one gets ‘high.’
CBD Dosage
Little study has been done on the ideal dosage of CBD. Generally, CBD products have a suggested dose on the manufacturer’s label. If a person experiences any negative effects while using CBD, they should immediately cut the dosage or cease taking it.
Conclusion
For years, CBD has worked through certain conditions such as anxiety and depression, pain and inflammation, cancer therapy, anti-acne, and psychotic disorders. There are various forms of CBD in the market that can be utilized. To enjoy the benefits, find what works for you and stick to you. Most importantly, do not self-diagnose; consult a doctor or specialist to help you with the administration
References
Bergamaschi, M. M., Queiroz, R. H. C., Chagas, M. H. N., De Oliveira, D. C. G., De Martinis, B. S., Kapczinski, F., … & Crippa, J. A. S. (2011). Cannabidiol Reduces The Anxiety Induced By Simulated Public Speaking In Treatment-Naive Social Phobia Patients. Neuropsychopharmacology, 36(6), 1219-1226.
Di Marzo, V., & Piscitelli, F. (2015). The Endocannabinoid System And Its Modulation By Phytocannabinoids. Neurotherapeutics, 12(4), 692-698.
Fernández‐Ruiz, J., Sagredo, O., Pazos, M. R., García, C., Pertwee, R., Mechoulam, R., & Martínez‐Orgado, J. (2013). Cannabidiol For Neurodegenerative Disorders: Important New Clinical Applications For This Phytocannabinoid?. British Journal Of Clinical Pharmacology, 75(2), 323-333.
Graczyk, M., Łukowicz, M., & Dzierzanowski, T. (2021). Prospects For The Use Of Cannabinoids In Psychiatric Disorders. Frontiers In Psychiatry, 12, 620073.
Hurd, Y. L., Yoon, M., Manini, A. F., Hernandez, S., Olmedo, R., Ostman, M., & Jutras-Aswad, D. (2015). Early Phase In The Development Of Cannabidiol As A Treatment For Addiction: Opioid Relapse Takes Center Stage. Neurotherapeutics, 12(4), 807-815
Jadoon, K. A., Ratcliffe, S. H., Barrett, D. A., Thomas, E. L., Stott, C., Bell, J. D., … & Tan, G. D. (2016). Efficacy And Safety Of Cannabidiol And Tetrahydrocannabivarin On Glycemic And Lipid Parameters In Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Pilot Study. Diabetes Care, 39(10), 1777-1786.
Millar, S. A., Stone, N. L., Bellman, Z. D., Yates, A. S., England, T. J., & O’Sullivan, S. E. (2019). A Systematic Review Of Cannabidiol Dosing In Clinical Populations. British Journal Of Clinical Pharmacology, 85(9), 1888-1900.
Peyravian, N., Deo, S., Daunert, S., & Jimenez, J. J. (2022). The Anti-Inflammatory Effects Of Cannabidiol (CBD) On Acne. Journal Of Inflammation Research, 15, 2795.
Seltzer, E. S., Watters, A. K., Mackenzie Jr, D., Granat, L. M., & Zhang, D. (2020). Cannabidiol (CBD) As A Promising Anti-Cancer Drug. Cancers, 12(11), 3203.
Vandolah, H. J., Bauer, B. A., & Mauck, K. F. (2019, September). Clinicians’ Guide To Cannabidiol And Hemp Oils. In Mayo Clinic Proceedings (Vol. 94, No. 9, Pp. 1840-1851). Elsevier.
Weiss, L., Zeira, M., Reich, S., Har-Noy, M., Mechoulam, R., Slavin, S., & Gallily, R. (2006). Cannabidiol Lowers The Incidence Of Diabetes In Non-Obese Diabetic Mice. Autoimmunity, 39(2), 143-151.
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